Categories
Medicine and Health

What should be discussed when talking to john about the potential issues when choosing home hd over in-centre hd

Objective
You are tasked to provide a case study that details the most important considerations in taking a patient on their journey from the “Advanced Kidney Care Clinic” to being treated on home haemodialysis.
Assignment brief
John is 52 years old and has diabetic kidney disease. He has been under the care of the hospital renal team who regularly monitor his kidney function. He spent several years in the “General nephrology” clinic, before moving to the “Advanced Kidney Care Clinic” which is focused on preparing patients for when their kidney function reduces so much that Renal Replacement Therapy is needed.
John is still working, tries to stay active and enjoys spending time with his children and grandchildren. He has high blood pressure, despite efforts to control it with medication. His biochemistry shows consistently high potassium levels, even though he has received dietetic advice to try and reduce his potassium intake.
John’s kidney Consultant has indicated that his kidney function has dropped to a level where they need to start talking about Renal Replacement Therapy. We would like you to describe the important things that should be considered as John transitions from a patient in the Advanced Kidney Care clinic to being an independent home haemodialysis patient. Things you should include are:
1. Creation of appropriate vascular access
2. What should be discussed when talking to John about the benefits to choosing home HD over in-centre HD
3. What should be discussed when talking to John about the potential issues when choosing home HD over in-centre HD
4. Decisions around the frequency and length of dialysis
5. The dialysis prescription (think about what level of solutes to add to the dialysis fluid)
6. Dialysis equipment required
7. Possible complications with haemodialysis and Safety systems of equipment
8. Commissioning of dialysis equipment
9. Water testing/Good practice
10. Maintaining high quality after installation, equipment, safety, testing, water.
Reminders
– You can assume that the audience who the presentation is aimed at has a good understanding of renal failure and haemodialysis.
– You can get a significant proportion of marks simply for making sure your presentation is easy to read, formatted well, has appropriate references and has a logical flow and structure.
– The rest of the marks will be divided between each of the ten sections outlined above, with higher marks for more comprehensive and relevant information (i.e. things that are particularly important to think about for home haemodialysis rather than just for dialysis in general)
Length:
2000-3000 words. Relevant images, tables or graphs can be included to help illustrate the points you are making. (renal technology)
The Learning Objectives to be assessed in this assignment are as follows:-
1. Knowledge & Understanding
Understand the biology of the kidney and its pathology.
Understand the principles of renal replacement therapy
Critically evaluate healthcare technologies for renal dialysis systems.
Understand the principles of infection control in the dialysis unit
2. Discipline Skills
Exercise significant judgement in the context of integrated and multidisciplinary healthcare technology
3. Personal Transferable Skills
Apply scientific method; solve problems systematically

Categories
Medicine and Health

In 750 words of less, describe how as a certified cardiovascular perfusionist (ccp) you will utilize evidence based medicine (ebm) in your daily practice

In 750 words of less, describe how as a certified cardiovascular perfusionist (CCP) you will utilize evidence based medicine (EBM) in your daily practice

Categories
Medicine and Health

What should be discussed when talking to john about the potential issues when choosing home hd over in-centre hd

Objective
You are tasked to provide a case study that details the most important considerations in taking a patient on their journey from the “Advanced Kidney Care Clinic” to being treated on home haemodialysis.
Assignment brief
John is 52 years old and has diabetic kidney disease. He has been under the care of the hospital renal team who regularly monitor his kidney function. He spent several years in the “General nephrology” clinic, before moving to the “Advanced Kidney Care Clinic” which is focused on preparing patients for when their kidney function reduces so much that Renal Replacement Therapy is needed.
John is still working, tries to stay active and enjoys spending time with his children and grandchildren. He has high blood pressure, despite efforts to control it with medication. His biochemistry shows consistently high potassium levels, even though he has received dietetic advice to try and reduce his potassium intake.
John’s kidney Consultant has indicated that his kidney function has dropped to a level where they need to start talking about Renal Replacement Therapy. We would like you to describe the important things that should be considered as John transitions from a patient in the Advanced Kidney Care clinic to being an independent home haemodialysis patient. Things you should include are:
1. Creation of appropriate vascular access
2. What should be discussed when talking to John about the benefits to choosing home HD over in-centre HD
3. What should be discussed when talking to John about the potential issues when choosing home HD over in-centre HD
4. Decisions around the frequency and length of dialysis
5. The dialysis prescription (think about what level of solutes to add to the dialysis fluid)
6. Dialysis equipment required
7. Possible complications with haemodialysis and Safety systems of equipment
8. Commissioning of dialysis equipment
9. Water testing/Good practice
10. Maintaining high quality after installation, equipment, safety, testing, water.
Reminders
– You can assume that the audience who the presentation is aimed at has a good understanding of renal failure and haemodialysis.
– You can get a significant proportion of marks simply for making sure your presentation is easy to read, formatted well, has appropriate references and has a logical flow and structure.
– The rest of the marks will be divided between each of the ten sections outlined above, with higher marks for more comprehensive and relevant information (i.e. things that are particularly important to think about for home haemodialysis rather than just for dialysis in general)
Length:
2000-3000 words. Relevant images, tables or graphs can be included to help illustrate the points you are making. (renal technology)
The Learning Objectives to be assessed in this assignment are as follows:-
1. Knowledge & Understanding
Understand the biology of the kidney and its pathology.
Understand the principles of renal replacement therapy
Critically evaluate healthcare technologies for renal dialysis systems.
Understand the principles of infection control in the dialysis unit
2. Discipline Skills
Exercise significant judgement in the context of integrated and multidisciplinary healthcare technology
3. Personal Transferable Skills
Apply scientific method; solve problems systematically

Categories
Medicine and Health

How does antibiotic therapy apply to the surgical setting?

1. Introduction
a. history and purpose
b. pathogens associated with surgical site infections
2. Antimicrobial action
3. Antibiotic resistance
4. Antibiotic agents
a. Major groups of Antibiotics
i. Amnioglycosides
ii.Beta-lactams
iii. Penicillins
iv. Cephalosporins
v. Carbapenems
vi. Monobactams
vii. floroquinolones
viii. Macrolides
ix. tetracyclines
x. Miscellaneous Antibiotics (sulfa)
5. Conclusion
a. How does antibiotic therapy apply to the surgical setting?

Categories
Medicine and Health

How does antibiotic therapy apply to the surgical setting?

1. Introduction
a. history and purpose
b. pathogens associated with surgical site infections
2. Antimicrobial action
3. Antibiotic resistance
4. Antibiotic agents
a. Major groups of Antibiotics
i. Amnioglycosides
ii.Beta-lactams
iii. Penicillins
iv. Cephalosporins
v. Carbapenems
vi. Monobactams
vii. floroquinolones
viii. Macrolides
ix. tetracyclines
x. Miscellaneous Antibiotics (sulfa)
5. Conclusion
a. How does antibiotic therapy apply to the surgical setting?

Categories
Medicine and Health

Explain your motivation to seek a career in medicine.

So I need help completing a personal statement for med school. I can give you a general idea of what I want in it. This is the essay prompt. Explain your motivation to seek a career in MEDICINE. Be sure to include the value of your experiences that prepare you to be a physician. It is 5000 characters including spaces.

Categories
Medicine and Health

Explain your motivation to seek a career in medicine.

So I need help completing a personal statement for med school. I can give you a general idea of what I want in it. This is the essay prompt. Explain your motivation to seek a career in MEDICINE. Be sure to include the value of your experiences that prepare you to be a physician.

Categories
Medicine and Health

Explain your motivation to seek a career in medicine.

So I need help completing a personal statement for med school. I can give you a general idea of what I want in it. This is the essay prompt. Explain your motivation to seek a career in MEDICINE. Be sure to include the value of your experiences that prepare you to be a physician.

Categories
Medicine and Health

Explain your motivation to seek a career in medicine.

So I need help completing a personal statement for med school. I can give you a general idea of what I want in it. This is the essay prompt. Explain your motivation to seek a career in MEDICINE. Be sure to include the value of your experiences that prepare you to be a physician. It is 5000 characters including spaces.

Categories
Medicine and Health

However, if you choose to amend the template format, be sure that your assignment is adequately spaced, spell checked, and maintains one-inch margins.

Background: One of the ways by which industry and the general public (i.e., any interested person) can influence the commercial/regulatory framework is via Citizen’s Petitions.
Citizen’s Petitions are requests that are formally submitted to the FDA Commissioner to ask the Commissioner to establish, amend, or revoke a regulation or order or take or refrain from taking any other form of administrative action. Essentially, one is making an appeal (with some statement of grounds/rationale) to request that the FDA take a certain action/uphold a certain position on an issue.
If interested, you can read a bit more about Citizen’s Petitions here: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=10.3 Links to an external site. and https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?FR=10.30 Links to an external site.
Your assignment: Use the template provided and choose one of the arguments below to write a Citizen’s Petition based on Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno- and homografts (THIS PAPER IS ATTACHED):
• Make a case for why the FDA’s expedited programs for regenerative medicines (from the reading assignment: “Expedited Programs for Regenerative Medicine Therapies for Serious Conditions: Guidance for Industry”) are adequately designed and good for promoting the development of cell, gene, or tissue engineering products (choose according to the subject of your journal club article). Utilize the safety and/or efficacy data presented in your Journal Club article to support your case.
OR
• Make a case for why the FDA’s expedited programs for regenerative medicines (per the attached reading: “Expedited Programs for Regenerative Medicine Therapies for Serious Conditions: Guidance for Industry”) are inadequate to facilitate the FDA’s thorough review and regulation of cell, gene, or tissue engineering products and/or may lead to the development of unsafe/ineffective cell, gene, or tissue engineering products (choose according to the subject of your journal club article). Utilize the safety and/or efficacy data presented in your Journal Club article to support your case.

PLEASE NOTE: You will need to request a specific action from the FDA – which will require some thought and creativity on your part. You can be as specific as you like with the topic of your petition, as long as it fits within the context of one of the points above. For example, you could request that FDA grant (if it is a case that wouldn’t otherwise qualify)/deny (if it may qualify and you believe it isn’t safe/wise for the pathway to be available to it) regenerative medicine advanced therapy (RMAT) designation to the product/products like the one you covered. You could also seek a policy change – perhaps a pathway for more in-depth review/even more abbreviated review due to the complexity/simplicity of product.
You may also find it helpful to refer to other sources or additional course materials (e.g., some of the scientific rationale, explanations of therapeutic promise offered by different regenerative medicines, and/or or critiques of the FDA’s review process) in formulating a convincing argument.
To successfully complete this assignment you will expected to:
• publish a petition with all required sections (per the template provided)
• Clearly articulate a requested action that is in line with the scope of the assignment
• Construct a sound case to support the requested action, which:
• Incorporates the journal club topic
• Is logically written and relevant to the requested action
Format, grammar, and overall presentation are also graded aspects of this assignment. Remember, the FDA Commissioner is the intended audience; write this as if the Commissioner were actually reading it. The assignment should be submitted as a well-written document with clearly expressed points, typed in Microsoft Word using 11-point Arial font. You can just edit the text within the provided template. However, if you choose to amend the template format, be sure that your assignment is adequately spaced, spell checked, and maintains one-inch margins. This assignment can reasonably be completed within 5 pages but I will accept up to a total length of 15 pages – remember: a lengthy assignment does not necessarily equate to a quality assignment; extra information will not earn you extra points (in fact, it may cause you to lose points)!

This written assignment should be uploaded and submitted before midnight NOV 18th
Note: Please be sure to complete this assignment in line with the Code of Conduct and applicable Ethics policies. All references must be documented accordingly.

Additional Resources
The following site provides actual petitions:
https://www.fda.gov/about-fda/cdrh-foia-how-get-records-cdrh/cdrh-petitions Links to an external site.
Explanation of Citizen’s Petitions: Comment on Proposed Regulations and Submit Petitions
https://www.fda.gov/regulatory-information/dockets-management/comment-proposed-regulations-and-submit-petitions Links to an external site.